ALS Centre CHU Bretonneau

Care Missions

1. Consultation of recourse for MND
2. Management of MND patients from diagnosis to last stages
3. Quaterly Multidisciplinary follow-up of MND patients
4. Coordonation of  medical, paramedical and social support at home in collaboration with the NeuroCentre Networ

Research

Genetics

• Identification of susceptibility factors of ALS
• Setup of next generation sequencing

Biomarkers

• Identification of CSF and blood biomarkers for the diagnostic and the pronostic of ALS using metabolomics
• Energetic metabolism exploration (calorimetry, functional exploration of fibroblasts…) : ongoing

Clinical Trials

1. Contribution to clinical trials
2. Development of pharmacogenomics

We are also developing scientific projects on Molecular Imaging focused on neuro-inflammation.

We are setting-up a ALS Registry in the Centre Val de Loire which is an extension of the Registry of the Limousin

Communications and Publications of the results of our studies during French and International ALS Meeting and into national and international reviews.