Ljubljana ALS Centre

    Foundation year2002
    DirectorProfessor Janez Zidar
    Principal investigatorProfessor Janez Zidar

    The centre was established in 2002 at the Institute of Clinical Neurophysiology, University Medical Centre Ljubljana. The multidisciplinary team offers clinical care for most of the Slovenian patients with ALS. The main research interests include neurophysiology and neuroimaging of ALS. The centre hosted the ENCALS meeting of 2017.

    Contact Information

    AddressLjubljanaZaloška 7SI-1000 Slovenia

    ContactDr Blaž Koritnik

    Restricted information

    Serving population
    >1.000.000

    Patient resources

    Population based register
    Clinic based register
    Geographically matched controles
    Number of muscle samples
    0
    Number of skin samples
    0
    Number of spinal cord samples
    0
    Number of brain samples
    0
    Number of IPS cell samples
    0

    Banks

    TypeALS PatientsControlsOther
    DNA Bank
    100
    0
    0
    CSF Bank
    65
    0
    0
    Serum Bank
    65
    0
    0
    RNA Bank
    0
    0
    0

    Research activities

    Clinical management research
    Neuro epidemiology
    Neuro physiology
    Neuro imaging
    Neuro psychology
    Neuro pathology
    Genomics
    Transcriptomics
    Metabolomics

    Publication

    • Kirbis M, Koritnik B, Leonardis L, Groselj LD, Klinar P, Kovacic SR, Zidar J. Amyotrophic lateral sclerosis in Slovenia – analysis of a patient cohort at the Ljubljana Institute of Clinical Neurophysiology. Zdrav Vestn. 2015 Jul-Aug;84(7):528-35. http://vestnik.szd.si/index.php/ZdravVest/article/view/1273/1055
    • Vrabec K, Koritnik B, Leonardis L, Dolenc-Groselj L, Zidar J, Smith B, et al. Genetic analysis of amyotrophic lateral sclerosis in the Slovenian population. Neurobiol Aging. 2015 Mar;36(3):1601.e17-20. doi: 10.1016/j.neurobiolaging.2014.11.011.
    • Bizovicar N, Dreo J, Koritnik B, Zidar J. Decreased movement-related beta desynchronization and impaired post-movement beta rebound in amyotrophic lateral sclerosis. Clin Neurophysiol. 2014 Aug;125(8):1689–99. doi: 10.1016/j.clinph.2013.12.108.
    • Leonardis L, Dolenc Groselj L. Non-invasive positive-pressure ventilation in patients with amyotrophic lateral sclerosis: spinal versus bulbar form. Eur J Neurol. 2013 May;20(5):e66–e66. doi: 10.1111/ene.12105.
    • Bizovicar N, Koritnik B, Zidar I, Dreo J, Zidar J. Movement-related cortical potentials in ALS increase at lower and decrease at higher upper motor neuron burden scores. Amyotroph Lateral Scler Frontotemporal Degener. 2013 Jan 18;1–10. doi: 10.3109/21678421.2012.760604.