The LAGENBIO (TERAGEN Y REGENERAGEN) Group, University of Zaragoza
Instituto de Investigación Sanitaria de Aragón-LAGENBIO (TERAGEN Y REGENERAGEN)
The LAGENBIO (TERAGEN Y REGENERAGEN) Group is one of the most experienced research group on ALS in Spain since 1998 and it is a reference center in Aragon. Our group is a multidisciplinary team that will collaborate very closely to the next coming Neuromuscular Clinical Unit in Aragon. One of our main aims deals with the identification and validation of novel prognostic and diagnostic biomarkers of disease to enhance translational studies from the animal model to the ALS patient, and to develop preclinical and clinical assays. In addition, the LAGENBIO Group has also wide expertise of innovative therapeutic approaches at preclinical level.
Contact Information
AddressZaragozaMiguel Servet, 17750006 Spain
ContactUniversity of Zaragoza
Restricted information
Patient resources
Banks
Research activities
Publication
- Rando A, Pastor D, Viso-León MC, Martínez A, Manzano R, Navarro X, Osta R, Martínez S. Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1(G93A) mice and modulates expression of prognosis biomarkers of the disease. Stem Cell Res Ther. 2018 Apr 6;9(1):90.
- Gasco S, Zaragoza P, García-Redondo A, Calvo AC, Osta R. Inflammatory and non-inflammatory monocytes as novel prognostic biomarkers of survival in SOD1G93A mouse model of Amyotrophic Lateral Sclerosis. PLoS One. 2017 Sep 8;12(9):e0184626
- Gasco S, Rando A, Zaragoza P, García-Redondo A, Calvo AC, Osta R. Comparative study of hematopoietic stem and progenitor cells between sexes in mice under physiological conditions along time. Cell Biol Int. 2017 Dec;41(12):1399-1405.
- Larrodé P, Calvo AC, Moreno-Martínez L, de la Torre M, Moreno-García L, Molina N, Castiella T, Iñiguez C, Pascual LF, Mena FJM, Zaragoza P, Y Cajal SR, Osta R. DREAM-Dependent Activation of Astrocytes in Amyotrophic Lateral Sclerosis. Mol Neurobiol. 2018 Jan;55(1):1-12.
- Uffo O, Martínez N, Acosta A, Sanz A, Martín-Burriel I, Osta R, Rodellar C, Zaragoza P. Analysis of microsatellite markers in a Cuban water buffalo breed. J Dairy Res. 2017 Aug;84(3):289-292.