Universitätsklinikum Carl Gustav Carus Dresden and the Technische Universität Dresden

The University Outpatient Clinic for Motor Neurone Diseases at the University Hospital Carl Gustav Carus Dresden serves patients with amyotrophic lateral sclerosis and its variants, spinal muscular atrophy, hereditary spastic spinal paralysis and other motor neurone diseases. We offer diagnostic classification (including electrophysiology, imaging procedures, lumbar puncture with biomarker analysis, etc.), second opinion and multidisciplinary therapy support for patients with motor neurone diseases. Our centre has vast experience delivering gene therapeutics (nusinersen, risdiplam and tofersen). In addition to patient care, scientific research is important to us. Patients at our centre are, therefore, invited to participate in clinical trials of drug candidates as well as research studies, which currently focus on biomarker research, treatment efficacy and drug treatment side effects as well as on the improvement of palliative patient care.

The Technische Universität Dresden, particularly at the Center for Regenerative Therapies TU Dresden (CRTD), utilizes patient-derived induced pluripotent stem (iPS) cells in combination with animal models to identify molecular mechanisms of disease pathogenesis as well as novel therapeutic targets to treat motor neurone diseases.