ALS CLINIC – LISBON (Centro Hospitalar Lisboa)

The ALS-Clinic in Lisbon has initiated its activities in 1985. Since then has been devoted to the care of ALS patients, mostly from Lisbon area, but also to many patients living in other regions of the country. In addition to clinical activities this center has been doing continous clinical and neurophysiological research, in particular on electrophysiological diagnosis, measurement of disease progression, and respiratory changes and its treatment. More recently, we have develloped other areas of research, as molecular biomarkers.

ALS CLINIC – LISBON (Centro Hospitalar Lisboa)
Foundation year

1983

Director

Mamede de Carvalho

Principal investigator

Mamede de Carvalho

Contact information
Address

Department of Neurosciences and Mental Health, Centro Hospitalar
LisboaNorte-Hospital de Santa Maria. Av. Prof Egas Moniz
1649-028, Lisbon
Portugal

Contact

Prof Mamede de Carvalho

Phone

+ 351 21 7805219

Fax

+ 351 21 7805219

Email mamedemg@netcabo.pt

Publications

  • De Carvalho, M., Turkman, A., Pinto, S., Swash, M. (2016). Modulation of fasciculation frequency in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 87:226-228.
  • Pinto, S., Alves, P., Pimentel, B., Swash, M., de Carvalho, M (2016). Ultrasound for assessment of diaphragm in ALS. Clin Neurophysiol 127:892-897.
  • Londral, A., Pinto, A., Pinto, S., Azevedo, L., de Carvalho, M. (2016). Markers for upper limb dysfunction in Amyotrophic Lateral Sclerosis using analysis of typing activity. Clin Neurophysiol 127: 925-931.
  • Costa, J., de Carvalho, M. (2016). Emerging molecular biomarker targets for amyotrophic lateral sclerosis. ¬†Clin Chim Acta 455: 7-14
  • De Carvalho, M., Swash, M. (2016). Lower motor neuron dysfunction in ALS. Clin Neurophysiol 127:2670-2681.

Find more publications of Prof Mamede de Carvalho via PubMed.

 

Restricted information

Serving population
Serving population

3.000.000

Patient resources
Population based register

No

Clinic based register

Yes

Geographically matched controls

Yes

Banks

Type ALS Patients Controls Other
Plasma 200 100
CSF Biobank 80 50
Research activities
Clinical management research

Yes

Neuro epidemiology

No

Neuro physiology

Yes

Neuro imaging

Yes

Neuro psychology

No

Neuro pathology

No

Genomics

Yes

Transcriptomics

No

Metabolomics

Yes

Clinical Trials - Industry sponsored

Name Type Patients
Combination with riluzole in the treatment of patients suffering from ALS AB10015 (2016-2017) 3
Ventilatory investigation of tirasemtiv and assessment of longitudinal after treatment for a year Vitality (2016-2017) 5

Clinical Trials - Investigator initiated

There are no clinical trials for this centre