Our ALS Unit attends 150 patients/year, being the reference Unit for ALS in the Valencian region (5.000.000 inhabitants). Our ALS research group is part of the research group on neuromuscular diseases and ataxias and is integrated in the spanish rare diseases network (CIBERER). Our main research interests are the genetic characterization of our patient cohort and the search of neuroimaging biomarkers.
| ALS Unit, Neurology Department, Hospital Universitari i Politècnic La Fe | |
|---|---|
| Foundation year | 2014 |
| Director | Teresa Sevilla |
| Principal investigator | Juan F Vázquez-Costa |
| Contact information | |
|---|---|
| Address | Avda Fernando Abril Martorell 106-Torre D, 5 |
| Contact | +34961245542 |
| Phone | +34961245542 |
| Fax | +34961246241 |
| vazquez_juacos@gva.es | |
| Website | Visit the website |
Publications
Publications can be viewed via the profile of Juan Vázquez-Costa.
- Vázquez-Costa JF, Alabajos A, Guevara M, Roda C, Sevilla T. Safety and efficacy of botulinum toxin A for the treatment of spasticity in amyotrophic lateral sclerosis: results of a pilot study. J Neurol. 2016;263(10):1954-60.
- Vázquez-Costa JF, Bataller L, Vílchez JJ. Primary lateral sclerosis and hereditary spastic paraplegia in sporadic patients. Ann Neurol. 2016:24671. doi:10.1002/ana.24671.
- Arlandis S, Vázquez-Costa JF, Martínez-Cuenca E, Sevilla T, Boronat F, Broseta E. Urodynamic findings in amyotrophic lateral sclerosis patients with lower urinary tract symptoms: Results from a pilot study. Neurourol Urodyn. 2016. doi:10.1002/nau.22976.
- Vázquez-Costa JF, Beltrán E, Sopena P, et al. Clinical and neuroimaging characterization of two C9orf72-positive siblings with amyotrophic lateral sclerosis and schizophrenia. Amyotroph Lateral Scler Frontotemporal Degener. 2015:1–4. doi:10.3109/21678421.2015.1112407.
- Dols-Icardo O, Nebot I, Gorostidi A, et al. Analysis of the CHCHD10 gene in patients with frontotemporal dementia and amyotrophic lateral sclerosis from Spain. Brain. 2015:awv175. doi:10.1093/brain/awv175.
Restricted information
| Serving population | |
|---|---|
| Serving population | 100.000 to 1.000.000 |
| Patient resources | |
|---|---|
| Population based register | No |
| Clinic based register | Yes |
| Geographically matched controls | No |
| Number of muscle samples | 20 |
Banks
| Type | ALS Patients | Controls | Other |
|---|---|---|---|
| DNA Bank | 220 | 0 | 8 |
| CSF Bank | 60 | 0 | 0 |
| Serum Bank | 220 | 0 | 8 |
| Research activities | |
|---|---|
| Clinical management research | Yes |
| Neuro epidemiology | No |
| Neuro physiology | Yes |
| Neuro imaging | Yes |
| Neuro psychology | No |
| Neuro pathology | No |
| Genomics | Yes |
| Transcriptomics | No |
| Metabolomics | No |
Clinical Trials - Industry sponsored
There are no clinical trials for this centre
Clinical Trials - Investigator initiated
There are no clinical trials for this centre