The ALS Centre at IRCCS Ospedale Policlinico San Martino is the regional referral Centre for ALS and other motor neuron diseases (MNDs) in Liguria, Italy. The structure includes in and out-patient fully equipped clinics staffed by a multidisciplinary team of experts constantly involved in early diagnosis, management and treatment of MNDs. To successfully pursue these objectives the Centre has adopted a multimodal translational research approach integrating clinical, genetic, MRI, cognitive and biofluid markers.
| IRCCS Ospedale Policlinico San Martino | |
|---|---|
| Foundation year | 1923 |
| Director | Dr. Claudia Caponnetto |
| Principal investigator | Dr. Claudia Caponnetto, Dr. Pilar M. Ferraro, Dr. Giuseppe Meo |
| Contact information | |
|---|---|
| Address | Largo P. Daneo 3 |
| Contact | Dr. Pilar M. Ferraro / Dr. Claudia Caponnetto |
| Phone | 0039 010 555 7290 |
| PilarMaria.Ferraro@ext.unige.it / ccaponnetto@neurologia.unige.it | |
| Website | Visit the website |
Publications
- Cabona C, Ferraro PM, Meo G, Roccatagliata L, Schenone A, Inglese M, Villani F, Caponnetto C. Predictors of self-perceived health worsening over COVID-19 emergency in ALS. Neurol Sci. 2021. doi: 10.1007/s10072-020-04997-z.
- Ferraro PM, Cabona C, Meo G, Rolla-Bigliani C, Castellan L, Pardini M, Inglese M, Caponnetto C, Roccatagliata L. Age at symptom onset influences cortical thinning distribution and survival in Amyotrophic Lateral Sclerosis. Neuroradiology 2021. doi:10.1007/s00234-021-02681-3.
- Ferraro PM, Campi C, Miceli A, Rolla-Bigliani C, Bauckneht M, Gualco L, Piana M, Marini C, Castellan L, Morbelli S, Caponnetto C, Sambuceti G, Roccatagliata L. 18 F-FDG-PET correlates of aging and disease course in ALS as revealed by distinct PVC approaches. DOI: 10.1016/j.ejro.2022.100394
Restricted information
| Serving population | |
|---|---|
| Serving population | 1.500.000 |
| Patient resources | |
|---|---|
| Population based register | Yes |
| Clinic based register | Yes |
| Geographically matched controls | No |
Banks
There are no banks for this centre
| Research activities | |
|---|---|
| Clinical management research | Yes |
| Neuro epidemiology | Yes |
| Neuro physiology | Yes |
| Neuro imaging | Yes |
| Neuro psychology | Yes |
| Neuro pathology | No |
| Genomics | Yes |
| Transcriptomics | No |
| Metabolomics | No |
Clinical Trials - Industry sponsored
There are no clinical trials for this centre
Clinical Trials - Investigator initiated
| Name | Type | Patients |
|---|---|---|
| Rapamycin Treatment for ALS (RAP-ALS) NCT03359538 | Phase II randomized, double-blind, placebo-controlled, multicenter clinical trial | 4 |
| The Effect of RNS60 on ALS Biomarkers. NCT03456882 | Multicenter, randomized, double-blind, placebo-controlled, parallel group, add-on phase II trial | 2 |
| PROTEIN MISFOLDING, AMYOTROPHIC LATERAL SCLEROSIS AND GUANABENZ: A PHASE II RCT WITH FUTILITY DESIGN | Phase II | 2 |