IRCCS Ospedale Policlinico San Martino

The ALS Centre at IRCCS Ospedale Policlinico San Martino is the regional referral Centre for ALS and other motor neuron diseases (MNDs) in Liguria, Italy. The structure includes in and out-patient fully equipped clinics staffed by a multidisciplinary team of experts constantly involved in early diagnosis, management and treatment of MNDs. To successfully pursue these objectives the Centre has adopted a multimodal translational research approach integrating clinical, genetic, MRI, cognitive and biofluid markers.

IRCCS Ospedale Policlinico San Martino
Foundation year

1923

Director

Dr. Claudia Caponnetto

Principal investigator

Dr. Claudia Caponnetto, Dr. Pilar M. Ferraro, Dr. Giuseppe Meo

Contact information
Address

Largo P. Daneo 3
16132 Genoa, Italy

Contact

Dr. Pilar M. Ferraro / Dr. Claudia Caponnetto

Phone

0039 010 555 7290

Email PilarMaria.Ferraro@ext.unige.it / ccaponnetto@neurologia.unige.it
Website Visit the website

Publications

  • Cabona C, Ferraro PM, Meo G, Roccatagliata L, Schenone A, Inglese M, Villani F, Caponnetto C. Predictors of self-perceived health worsening over COVID-19 emergency in ALS. Neurol Sci. 2021. doi: 10.1007/s10072-020-04997-z.
  • Ferraro PM, Cabona C, Meo G, Rolla-Bigliani C, Castellan L, Pardini M, Inglese M, Caponnetto C, Roccatagliata L. Age at symptom onset influences cortical thinning distribution and survival in Amyotrophic Lateral Sclerosis. Neuroradiology 2021.

    doi:10.1007/s00234-021-02681-3.

Restricted information

Serving population
Serving population

1.500.000

Patient resources
Population based register

Yes

Clinic based register

Yes

Geographically matched controls

No

Banks

There are no banks for this centre

Research activities
Clinical management research

Yes

Neuro epidemiology

Yes

Neuro physiology

Yes

Neuro imaging

Yes

Neuro psychology

Yes

Neuro pathology

No

Genomics

Yes

Transcriptomics

No

Metabolomics

No

Clinical Trials - Industry sponsored

There are no clinical trials for this centre

Clinical Trials - Investigator initiated

Name Type Patients
Rapamycin Treatment for ALS (RAP-ALS) NCT03359538 Phase II randomized, double-blind, placebo-controlled, multicenter clinical trial 4
The Effect of RNS60 on ALS Biomarkers. NCT03456882 Multicenter, randomized, double-blind, placebo-controlled, parallel group, add-on phase II trial 2
PROTEIN MISFOLDING, AMYOTROPHIC LATERAL SCLEROSIS AND GUANABENZ: A PHASE II RCT WITH FUTILITY DESIGN Phase II 2