The Leuven ALS center combines the diagnosis and multidisciplinary care for ALS and ALS/FTLD patients with clinical and basic research activities. Clinical research activities include genetic, imaging, electrophysiological and biomarker studies, as well as phase I-III clinical trials (P. Van Damme, MD, PhD). Basic research activities include generation of small animal models, rodent models and stem cell models for ALS and FTLD, and use them to identify and validate molecular targets for the treatment of these diseases (W. Robberecht MD, PhD, P. Van Damme, MD, PhD, and L. Van Den Bosch, PhD).
| KU Leuven – University of Leuven and VIB Leuven, Belgium | |
|---|---|
| Foundation year | 1997 |
| Director | Neuromuscular Reference Center: P. Van Damme, MD, PhD – VIB Laboratory of Neurobiology: L. Van Den Bosch, PhD |
| Principal investigator | P. Van Damme MD, PhD; L. Van Den Bosch, PhD & W. Robberecht, MD, PhD |
| Contact information | |
|---|---|
| Address | Laboratory of Neurobiology |
| Contact | Annelies Thuriot |
| Phone | +32 16 37 48 90 |
| annelies.thuriot@kuleuven.vib.be | |
| Website | Visit the website |
Publications
Publications can be viewed via this link.
Search for publications of Philip van Damme, Wim Robberecht and Ludo van den Bosch
Restricted information
| Serving population | |
|---|---|
| Serving population | 3.000.000 |
| Patient resources | |
|---|---|
| Population based register | No |
| Clinic based register | Yes |
| Geographically matched controls | Yes |
| Number of skin samples | 30 |
| Number of spinal cord samples | 20 |
| Number of brain samples | 20 |
| Number of IPS cell samples | 20 |
Banks
| Type | ALS Patients | Controls | Other |
|---|---|---|---|
| DNA Bank | 800 | 500 | 0 |
| Research activities | |
|---|---|
| Clinical management research | Yes |
| Neuro epidemiology | Yes |
| Neuro physiology | Yes |
| Neuro imaging | Yes |
| Neuro psychology | No |
| Neuro pathology | No |
| Genomics | Yes |
| Transcriptomics | Yes |
| Metabolomics | No |
Clinical Trials - Industry sponsored
| Name | Type | Patients |
|---|---|---|
| Newron-Sweden sNN0029-003 | Newron-Sweden sNN0029-003 | 9 |
| AB Science-France | AB Science-France | 15 |
Clinical Trials - Investigator initiated
There are no clinical trials for this centre