Sussex MND Care Network

We have established an MND/ALS Care Center in Sussex. This is a network-based model of care linking local MND teams to ensure better care and to provide access to research, especially clinical trials. We are building a laboratory research team in collaboration with Brighton and Sussex Medical School, and will be involved in clinical trials, imaging and stem cell research.

The Sussex MND/ALS Research Group spans the Departments of Life Sciences (Sussex Neuroscience) at the University of Sussex, The Department of Clinical Neuroscience, Brighton and Sussex Medical School, Universities of Brighton and Sussex, UK, and the Brighton and Sussex University Hospitals Trust Regional Neurosciences Centre.

In 2016 we established the Sussex MND Care and Research Network, the 20th Care ‘Centre’ funded by the Motor Neurone Disease Association.

Our research focuses on the causes and consequences of MND using laboratory models with a focus on molecular trafficking and axonal transport (Dr Majid Hafezparast and team); experimental medicine approaches including biomarker discovery (Dr Hafezparast, Professor Sarah Newbury, collaborating with Professor Martin Turner, University of Oxford); neuroimaging (with Professor Mara Cercignani, BSMS, in collaboration with Professor Daniel Alexander and colleagues, University College London, and investigators in USA, Italy, and Germany); studies on cognition and behavioural aspects of MND (Dr Elamin and colleagues); and clinical trials (MIROCALS study, funded by the European Union (H2020 award of €6.9M from 2015-2019).

  • Professor Peter Nigel Leigh (Director)
  • Dr Marwa Elamin
  • Dr Basil Ridha
  • Dr Andreas Hiersche
  • Ms Louise Viney
  • Coordinator: Ms Rachel Thomson
Sussex MND Care Network
Foundation year

2016

Director

Professor PN Leigh

Principal investigator

Professor PN Leigh

Contact information
Address

Neurology Research Group, Trafford Centre for Biomedical Research
University of Sussex, Brighton and Sussex Medical School,
Falmer, Brighton BN1 9RY UK

Network Coordinator: Ms Rachel Thomson (r.thomson@bsms.ac.uk)

Phone

+44 (0)1273 876768 (PA, Ms Pat Butler)

Email p.leigh@bsms.ac.uk
Website Visit the website

Publications

 

Restricted information

Serving population
Serving population

1.500.0000 or more

Patient resources
Population based register

Yes

Clinic based register

Yes

Geographically matched controls

Yes

Banks

Type ALS Patients Controls Other
MICROCALS biobank since 2017
Research activities
Clinical management research

Yes

Neuro epidemiology

Yes

Neuro physiology

Yes

Neuro imaging

Yes

Neuro psychology

Yes

Neuro pathology

Yes

Genomics

Yes

Transcriptomics

Yes

Metabolomics

Yes

Clinical Trials - Industry sponsored

Name Type Patients
Ozanezumab in ALS Ozanezumab in ALS 10
Levosimendan LEVALS 5

Clinical Trials - Investigator initiated

Name Type Patients
MIROCALS (http://mirocals.eu/) MIROCALS
PNL Chief Investigator and Co-Coordinator with Dr G Bensimon, Paris and Nimes, France