Instituto de Investigación Sanitaria de Aragón-LAGENBIO (TERAGEN Y REGENERAGEN)
The LAGENBIO (TERAGEN Y REGENERAGEN) Group is one of the most experienced research group on ALS in Spain since 1998 and it is a reference center in Aragon. Our group is a multidisciplinary team that will collaborate very closely to the next coming Neuromuscular Clinical Unit in Aragon. One of our main aims deals with the identification and validation of novel prognostic and diagnostic biomarkers of disease to enhance translational studies from the animal model to the ALS patient, and to develop preclinical and clinical assays. In addition, the LAGENBIO Group has also wide expertise of innovative therapeutic approaches at preclinical level.
The LAGENBIO (TERAGEN Y REGENERAGEN) Group, University of Zaragoza | |
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Foundation year | 2000 |
Director | Rosario Osta Pinzolas |
Principal investigator | Rosario Osta Pinzolas |
Contact information | |
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Address | LAGENBIO. C |
Contact | Dr. Rosario Osta |
Phone | 0034761621 |
osta@unizar.es | |
Website | Visit the website |
Publications
- Rando A, Pastor D, Viso-León MC, Martínez A, Manzano R, Navarro X, Osta R, Martínez S. Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1(G93A) mice and modulates expression of prognosis biomarkers of the disease. Stem Cell Res Ther. 2018 Apr 6;9(1):90.
- Gasco S, Zaragoza P, García-Redondo A, Calvo AC, Osta R. Inflammatory and non-inflammatory monocytes as novel prognostic biomarkers of survival in SOD1G93A mouse model of Amyotrophic Lateral Sclerosis. PLoS One. 2017 Sep 8;12(9):e0184626
- Gasco S, Rando A, Zaragoza P, García-Redondo A, Calvo AC, Osta R. Comparative study of hematopoietic stem and progenitor cells between sexes in mice under physiological conditions along time. Cell Biol Int. 2017 Dec;41(12):1399-1405.
- Larrodé P, Calvo AC, Moreno-Martínez L, de la Torre M, Moreno-García L, Molina N, Castiella T, Iñiguez C, Pascual LF, Mena FJM, Zaragoza P, Y Cajal SR, Osta R. DREAM-Dependent Activation of Astrocytes in Amyotrophic Lateral Sclerosis. Mol Neurobiol. 2018 Jan;55(1):1-12.
- Uffo O, Martínez N, Acosta A, Sanz A, Martín-Burriel I, Osta R, Rodellar C, Zaragoza P. Analysis of microsatellite markers in a Cuban water buffalo breed. J Dairy Res. 2017 Aug;84(3):289-292.
Restricted information
Serving population | |
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Serving population | 1.3 million |
Patient resources | |
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Population based register | No |
Clinic based register | No |
Geographically matched controls | No |
Banks
There are no banks for this centre
Research activities | |
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Clinical management research | No |
Neuro epidemiology | No |
Neuro physiology | No |
Neuro imaging | No |
Neuro psychology | No |
Neuro pathology | No |
Genomics | No |
Transcriptomics | Yes |
Metabolomics | Yes |
Clinical Trials - Industry sponsored
There are no clinical trials for this centre
Clinical Trials - Investigator initiated
There are no clinical trials for this centre